DeCS Server - List Exact Term

Search on:	UBIQUITIN-PROTEIN LIGASE COMPLEXES
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DeCS

Descriptor English:

Ubiquitin-Protein Ligase Complexes

Descriptor Spanish:

Complejos de Ubiquitina-Proteína Ligasa

Descriptor Portuguese:

Complexos Ubiquitina-Proteína Ligase

Synonyms English:

Complexes, Ubiquitin-Protein Ligase
Ligase Complexes, Ubiquitin-Protein
Ubiquitin Protein Ligase Complexes

Tree Number:

Definition English:

Complexes of enzymes that catalyze the covalent attachment of UBIQUITIN to other proteins by forming a peptide bond between the C-terminal GLYCINE of UBIQUITIN and the alpha-amino groups of LYSINE residues in the protein. The complexes play an important role in mediating the selective-degradation of short-lived and abnormal proteins. The complex of enzymes can be broken down into three components that involve activation of ubiquitin (UBIQUITIN-ACTIVATING ENZYMES), conjugation of ubiquitin to the ligase complex (UBIQUITIN-CONJUGATING ENZYMES), and ligation of ubiquitin to the substrate protein (UBIQUITIN-PROTEIN LIGASES).

Indexing Annotation English:

History Note English:

2004

Allowable Qualifiers English:

Record Number:

38180

Unique Identifier:

D043743

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